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Evaluation of a New Commercial Microarray Platform for the Simultaneous Detection of β-Lactamase and mcr-1 and mcr-2 Genes in Enterobacteriaceae

机译:同时检测肠杆菌科细菌中β-内酰胺酶和mcr-1和mcr-2基因的新型商业微阵列平台的评价。

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In this work, we evaluated the performance of the new commercial CT103XL microarray system (Check-Points). In ~6.5 h (starting from culture strains) and for a cost ranging from 50 to 85€, this platform allows the detection of mcr-1 (including the variants from mcr-1.2 to mcr-1.7) and mcr-2 determinants. Along with them, clinically important class A, B, C, and D β-lactamase (bla) genes are simultaneously detected, as in the former version (CT103XL) that has demonstrated an overall accuracy of 94% (7).
机译:在这项工作中,我们评估了新型商用CT103XL微阵列系统(Check-Points)的性能。在约6.5小时内(从培养菌株开始),成本从50欧元到85欧元不等,该平台可检测mcr-1(包括从mcr-1.2到mcr-1.7的变体)和mcr-2决定簇。与它们一起,同时检测到临床上重要的A,B,C和D类β-内酰胺酶(bla)基因,就像以前的版本(CT103XL)一样,该基因已证明总体准确度> 94%(7)。

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