首页> 外文期刊>The Journal of Experomental Medicine >BIOCHEMICAL STUDY OF CELLULAR ANTIGEN-ANTIBODY REACTION IN TISSUE CULTURE
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BIOCHEMICAL STUDY OF CELLULAR ANTIGEN-ANTIBODY REACTION IN TISSUE CULTURE

机译:组织培养中细胞抗原-抗体反应的生物化学研究

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Decrease in the protease activity of the culture fluid observed at later stages of the antigen-antibody reaction is believed to be due to the release of an inhibitor by the cells. The inhibitor was submitted to partial purification: it is heat-stable, non-precipitated by trichloracetic acid and non-dialyzable. It inhibits certain cellular and tissue proteases and papain but is inactive against trypsin. It is suggested that the balance between protease and anti-protease released may determine the intensity, extent, and duration of certain sensitization phenomena.
机译:据信在抗原-抗体反应的后期观察到的培养液蛋白酶活性的降低是由于细胞释放了抑制剂。抑制剂需要进行部分纯化:它是热稳定的,不会被三氯乙酸沉淀并且不可透析。它抑制某些细胞和组织蛋白酶和木瓜蛋白酶,但对胰蛋白酶无活性。建议蛋白酶和抗蛋白酶释放之间的平衡可能决定某些致敏现象的强度,程度和持续时间。

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