Does Orexin B Infused into Nucleus Accumbens Affect Open Field Activity In Wistar Rats.

摘要

ABSTRACT Orexins, which have been located in several parts of brain particularly in the hypothalamus and parts of diencephalon were implicated role in ingestive behaviour, role in sleep, wakefulness and other modalities of activities in animals. Nucleus accumbens is a large nuclear mass involved in appetitive behaviour and addiction. In order to evaluate if the Orexinergic system in open field activity, we carried out studies by infusing Orexin B and its antagonist into nucleus accumbens, in Wi.