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首页> 外文期刊>RSC Advances >Triflic acid promoted solvent free synthesis of densely functionalized furans
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Triflic acid promoted solvent free synthesis of densely functionalized furans

机译:三氟乙酸促进无溶剂合成高官能度呋喃

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摘要

A simple, efficient and novel methodology has been developed for the synthesis of densely substituted furans mediated by triflic acid. The current protocol proceeds in a domino fashion, the initial step involves Friedel–Crafts arylation, followed by dehydrative cyclization. It is operationally simple and can be carried out under solvent free conditions.
机译:已经开发了一种简单,有效和新颖的方法来合成由三氟甲磺酸介导的密集取代的呋喃。当前的协议以多米诺骨牌方式进行,第一步涉及Friedel-Crafts芳基化,然后进行脱水环化。它操作简单,可在无溶剂条件下进行。

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