Helicobacter pylori infection in children with sickle cell disease: IgG versus combined IgA and IgG serology.

摘要

ABSTRACT Serological tests are cheap and non-invasive, so they are used in the diagnosis of Helicobacter pylori infection and more preferred than other invasive methods. Although the diagnostic utility of IgG antibodies to H. pylori is well established, the usefulness of IgA tests is less well documented. Determine the prevalence of H. pylori infection and find the frequency of IgA-positive IgG-negative cases in children with SCD, thus assessing the clinical utility of IgA testing in those pati.