Evaluation of the Synergistic Potential of the Combination of an Opioid and Non-Opioid Analgesic in Experimental Models of Pain.

摘要

ABSTRACT The purpose of this present work was to evaluate the antinociceptive efficacy of a combination of an opioid and a non-opioid analgesic in experimental models of nociceptive pain in swiss albino mice using established pharmacological models of pain. As of date, no single analgesic drug is considered perfect in the treatment of all types of pain. Each analgesic agent possesses some distinct advantages and disadvantages with respect to the others. Hence, the clinical outcomes might be imp.