Hepatoprotective Action of Andrographis peniculata Against Cisplatin Induced Toxicity in Mice: A Histological Study.

摘要

ABSTRACT Platinum complex cisplatin (CP) is one of the most potent drugs, widely used in chemotherapy against neoplasia. It is known to exhibit hepatotoxicity. The medicinal plant Andrographis peniculata (AP), used in this study is well known to be hepatoprotective. So we take this experiment to see the effect of AP extract against cisplatin induced hepatotoxicity in mice. Swiss albino female mice, randomly divided into six different groups. Group I was controls. Group IInd received single dose.