Characterization of type II thioesterases involved in natamycin biosynthesis in Streptomyces chattanoogensis L10

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Characterization of type II thioesterases involved in natamycin biosynthesis in Streptomyces chattanoogensis L10

机译：表征链霉菌L10链霉菌中纳他霉素生物合成的II型硫酯酶

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TheknownfunctionsoftypeIIthioesterases(TEIIs)intypeIpolyketidesynthases(PKSs)includeselectingofstarteracylunits,removalofaberrantextenderacylunits,releasingoffinalproducts,anddehydrationofpolyketideintermediates.Inthisstudy,wecharacterizedtwoTEIIs(ScnIandPKSIaTEII)fromStreptomyceschattanoogensisL10.DeletionofscnIinS.chattanoogensisL10decreasedthenatamycinproductionbyabout43%.BothScnIandPKSIaTEIIcouldremoveacylunitsfromtheacylcarrierproteins(ACPs)involvedinthenatamycinbiosynthesis.OurresultsshowthattheTEIIcouldplayimportantrolesinboththeinitiationstepandtheelongationstepsofapolyketidebiosynthesis;theintracellularTEIIsinvolvedindifferentbiosyntheticpathwayscouldcomplementeachother...

机译：TheknownfunctionsoftypeIIthioesterases（TEIIs）intypeIpolyketidesynthases（PKS的）includeselectingofstarteracylunits，removalofaberrantextenderacylunits，releasingoffinalproducts，anddehydrationofpolyketideintermediates.Inthisstudy，wecharacterizedtwoTEIIs（ScnIandPKSIaTEII）fromStreptomyceschattanoogensisL10.DeletionofscnIinS.chattanoogensisL10decreasedthenatamycinproductionbyabout43％.BothScnIandPKSIaTEIIcouldremoveacylunitsfromtheacylcarrierproteins（的ACP）involvedinthenatamycinbiosynthesis.OurresultsshowthattheTEIIcouldplayimportantrolesinboththeinitiationstepandtheelongationstepsofapolyketidebiosynthesis; theintracellularTEIIsinvolvedindifferentbiosyntheticpathwayscouldcomplementeachother ...

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《FEBS Letters》 |2014年第17期|共6页
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1. Characterization of type II thioesterases involved in natamycin biosynthesis in Streptomyces chattanoogensis L10 [J] . WangY.-Y., RanX.-X., ChenW.-B., FEBS letters. . 2014,第17期

机译：表征链霉菌L10链霉菌中纳他霉素生物合成的II型硫酯酶
2. Bidirectional Regulation of AdpA _ch in Controlling the Expression of scnRI and scnRII in the Natamycin Biosynthesis of Streptomyces chattanoogensis L10 [J] . Pin Yu, Qing-Ting Bu, Yi-Li Tang, Frontiers in Microbiology . 2018,第6期

机译：AdpA _{ch 的双向调控在纳他霉素生物合成链霉菌产链蛋白L10的纳他霉素生物合成中控制 scnRI 和 scnRII 的表达。}
3. Bidirectional Regulation of AdpA _ch in Controlling the Expression of scnRI and scnRII in the Natamycin Biosynthesis of Streptomyces chattanoogensis L10 [J] . Pin Yu, Qing-Ting Bu, Yi-Li Tang, Frontiers in Microbiology . 2018,第6期

机译：AdpA _{ch 的双向调控在纳他霉素生物合成链霉菌产链蛋白L10的纳他霉素生物合成中控制 scnRI 和 scnRII 的表达。}
4. Polyketide Biosynthesis beyond the Type I, II, and IIIPolyketide Synthase Paradigms: A Progress Report [C] . Ben Shen, Yi-Qiang Cheng, Steven D. Christenson, American Chemical Society . 2006

机译：聚酮化合物生物合成超出I型，II和IIIPolykete Synthase Paradigms：进度报告
5. Natural products biosynthesis: I. Geosmin biosynthesis in Streptomyces coelicolor A3(2) and Nostoc punctiforme PCC 73102. II. Pentalenolactone biosynthetic pathway in Streptomyces avermitilis. [D] . Jiang, Jiaoyang. 2009

机译：天然产物的生物合成：I. coelicolor链霉菌A3（2）和点状诺氏菌PCC 73102中的土臭素生物合成。阿维链霉菌中的戊烯戊内酯生物合成途径。
6. Bidirectional Regulation of AdpAch in Controlling the Expression of scnRI and scnRII in the Natamycin Biosynthesis of Streptomyces chattanoogensis L10 [O] . Pin Yu, Qing-Ting Bu, Yi-Li Tang, -1

机译：AdpAch双向调控在纳他霉素生物合成链霉菌L10合成中的scnRI和scnRII表达的控制。
7. Characterization of type II thioesterases involved in natamycin biosynthesis in Streptomyces chattanoogensis L10 [O] . Wang Yue-Yue, Ran Xin-Xin, Chen Wei-Bin, 2014

机译：表征链霉菌L10链霉菌中纳他霉素生物合成的II型硫酯酶

Characterization of type II thioesterases involved in natamycin biosynthesis in Streptomyces chattanoogensis L10

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