Effects of angiotensin-(1|[ndash]|7) blockade on renal function in rats with enhanced intrarenal Ang II activity

MARCELA BüRGELOVá; HERBERT J KRAMER; VLADIMíR TEPLAN; MONIKA THUMOVá; LUDěK ?ERVENKA

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Effects of angiotensin-(1|[ndash]|7) blockade on renal function in rats with enhanced intrarenal Ang II activity

机译：血管紧张素-（1 | n | 7）阻断对肾内Ang II活性增强的大鼠肾功能的影响

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Effects of angiotensin-(1–7) blockade on renal function in rats with enhanced intrarenal Ang II activity.BackgroundIncreasing evidence suggests that angiotensin-(1–7) [Ang-(1–7)] acts as an endogenous antagonist of Ang II when the renin-angiotensin system (RAS) is activated. In the present study, we therefore compared the effects of acute intrarenal (i.r.) Ang-(1–7) receptor blockade on renal function under conditions of normal and increased intrarenal Ang II concentration.

机译：血管紧张素-（1-7）阻断对肾内Ang II活性增强的大鼠肾功能的影响。背景越来越多的证据表明，血管紧张素-（1-7）[Ang-（1-7）]是Ang II的内源性拮抗剂激活肾素-血管紧张素系统（RAS）时。因此，在本研究中，我们比较了正常和升高的肾内Ang II浓度条件下急性肾内（i.r.）Ang-（1-7）受体阻滞对肾功能的影响。

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《Kidney international.》 |2005年第4期|共9页
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MARCELA BüRGELOVá; HERBERT J KRAMER; VLADIMíR TEPLAN; MONIKA THUMOVá; LUDěK ?ERVENKA;
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中图分类泌尿科学（泌尿生殖系疾病）;
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1. Effects of angiotensin-(1|[ndash]|7) blockade on renal function in rats with enhanced intrarenal Ang II activity [J] . MARCELA BüRGELOVá, HERBERT J KRAMER, VLADIMíR TEPLAN, Kidney international. . 2005,第4期

机译：血管紧张素-（1 | n | 7）阻断对肾内Ang II活性增强的大鼠肾功能的影响
2. AT1 receptor blockade prevents the increase in blood pressure and the augmentation of intrarenal ANG II levels in hypertensive Cyp1a1-Ren2 transgenic rats fed with a high-salt diet. [J] . Williams DE, Prieto MC, Mullins JJ, The American Journal of the Medical Sciences . 2010,第4期

机译：AT1受体阻滞可防止高血压和高盐饮食的Cyp1a1-Ren2转基因大鼠血压升高和肾内ANG II水平升高。
3. Renal functional responses to selective intrarenal renin inhibition in Cyp1a1-Ren2 transgenic rats with ANG II-dependent malignant hypertension [J] . HowardC.G., MitchellK.D. American Journal of Physiology . 2012,第1aPta2期

机译：CYP1a1-Ren2转基因大鼠ANG II依赖性恶性高血压对选择性肾内肾素抑制的肾功能反应
4. Functional Studies of AT1 Antagonist SII Analogues Reveal Selective Cell Signaling and Inhibition of Ang-II Mediated NHE3 Activation [C] . Minying Cai, Hua Xu, Zhihua Liu American Peptide Symposium . 2009

机译：AT1拮抗剂SiI类似物的功能研究显示选择性细胞信号和抑制Ang-II介导的NHE3活化
5. Cardiovascular and Renal Effects of ANG II and Nitric Oxide in the Newborn: Roles of AT1Rs and /or AT2Rs. [D] . Vinturache, Angela Elena. 2012

机译：ANG II和一氧化氮对新生儿的心血管和肾脏作用：AT1R和/或AT2R的作用。
6. AT1 RECEPTOR BLOCKADE PREVENTS THE INCREASE IN BLOOD PRESSURE AND THE AUGMENTATION OF INTRARENAL ANG II LEVELS IN HYPERTENSIVE Cyp1a1-Ren2 TRANSGENIC RATS FED A HIGH SALT DIET [O] . Dustyn E. Williams, Minolfa C. Prieto, John J. Mullins, -1

机译：AT1受体阻滞可防止血压的增加和高血压CYP1A1-REN2转基因大鼠中高盐饮食的高血压CYP1-REN2转基因大鼠的增强
7. Effects of angiotensin-(1–7) blockade on renal function in rats with enhanced intrarenal Ang II activity [O] . Bürgelová Marcela, Kramer Herbert J., Teplan Vladimír, 2005

机译：血管紧张素-（1-7）阻断对肾内Ang II活性增强的大鼠肾功能的影响
8. Intrarenal Regulating Mechanisms of Renal Function [R] . Thurau, K. 1968

机译：肾功能的肾内调节机制

Effects of angiotensin-(1|[ndash]|7) blockade on renal function in rats with enhanced intrarenal Ang II activity

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