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Graphic methods to determine the function of nucleic acid sequences

机译:确定核酸序列功能的图解方法

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摘要

We describe an interactive computer program (ANALYSEQ) that is used from a simple graphics terminal. The main purpose of the program is to determine the function of nucleic acid sequences but it also offers the simpler listing, searching and counting options. It contains methods to locate genes by looking for the effects that coding for a protein has on the coding sequence, to locate tRNA genes by looking for secondary structure and conserved bases, and methods to locate signals such as promoters. Techniques to identify unusual regions of sequence and to search for potential Z DNA-forming regions are also included. Most of the routines produce graphical output which gives ease of interpretation and allows superposition of several independent forms of analysis.
机译:我们描述了一种从简单图形终端使用的交互式计算机程序(ANALYSEQ)。该程序的主要目的是确定核酸序列的功能,但它也提供了更简单的列表,搜索和计数选项。它包含通过寻找蛋白质编码对编码序列的影响来定位基因的方法,通过寻找二级结构和保守碱基来定位tRNA基因的方法,以及定位信号(例如启动子)的方法。还包括鉴定序列异常区域并搜索潜在的Z DNA形成区域的技术。大多数例程产生图形输出,使解释容易,并允许几种独立形式的分析叠加。

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