Is hepcidin the star player in iron metabolism in chronic kidney disease|[quest]|

摘要

It is well known that abnormal iron metabolism contributes to the development of anemia in chronic kidney disease (CKD) patients. Hepcidin is a circulating peptide produced in the liver that regulates efflux of iron from the cells. Ashby et al. measured the serum level of hepcidin using a new assay. Although the new assay produced mixed results and needs to be verified, these data suggest that hepcidin is not the only star player in iron metabolism in CKD.