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Caustic Ingestion in the Elderly: Influence of Age on Clinical Outcome

机译:老年人苛性摄入:年龄对临床结果的影响

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Caustic poisonings are still associated with many fatalities. Studies focusing on the elderly are rare. The purpose of the present study was to compare the clinical outcomes of caustic ingestion injury in elderly and non-elderly adults with regard to gender, intent of exposure, substance ingested, severity of mucosal injury, complications, and mortality. Caustic substance exposures reported to the National Toxicological Information Centre in Slovakia during 1998–2015 were reviewed retrospectively. The patients were divided into two groups: the non-elderly (p = 0.041). The risk of fatal outcome in the elderly was increased by acid ingestion (OR = 7.822; p = 0.002), particularly hydrochloric acid (OR = 5.714, p = 0.006). The incidence of respiratory complications was almost two times higher in the elderly was 31.1% vs. 17.4% for the non-elderly (p = 0.037). Respiratory complications significantly correlated with an increased mortality rate (p = 0.001) in the elderly whereas there was no association between GI complications and mortality in the elderly (p = 0.480). Elderly patients with respiratory complications had the poorest clinical outcomes. The highest risk of complications and fatalities was observed in patients after hydrochloric acid ingestion. View Full-Text
机译:苛性中毒仍然与许多死亡有关。针对老年人的研究很少。本研究的目的是就性别,接触意向,摄入的物质,粘膜损伤的严重程度,并发症和死亡率,比较老年人和非老年人的苛刻性摄入损伤的临床结果。回顾性地回顾了1998-2015年间向斯洛伐克国家毒理学信息中心报告的腐蚀性物质暴露情况。将患者分为两组:非老年人(p = 0.041)。摄入酸(OR = 7.822; p = 0.002),尤其是盐酸(OR = 5.714,p = 0.006),会增加老年人的致命结局风险。老年人呼吸系统并发症的发生率几乎是老年人的两倍,为31.1%,而非老年人为17.4%(p = 0.037)。老年人的呼吸系统并发症与死亡率增加显着相关(p = 0.001),而胃肠道并发症与老年人死亡率之间没有关联(p = 0.480)。患有呼吸系统并发症的老年患者临床效果最差。摄入盐酸后,发生并发症和死亡的风险最高。查看全文

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