Synthesis of a Highly Functionalized Triquinane: Studies Towards a Total Synthesis of Subergorgic Acid and Its Analogues

Veljko Dragojlovic

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Synthesis of a Highly Functionalized Triquinane: Studies Towards a Total Synthesis of Subergorgic Acid and Its Analogues

机译：高度功能化的三喹烷的合成：舒伯有机酸及其类似物的全合成研究

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Reaction of enone (11) with the bifunctional Grignard reagent (7) in the presence of copper(I) bromide – dimethyl sulfide, followed by intramolecular alkylation of the resultant chloroketone (15) gave the tricyclic ketone (12). The tricyclic ketone (12) was transformed into the angular triquinane dienedione (9) by means of an 8-step sequence.

机译：烯酮（11）与双功能格氏试剂（7）在溴化铜（I）-二甲硫的存在下反应，然后将所得氯酮（15）进行分子内烷基化，得到三环酮（12）。三环酮（12）通过8步序列转变成角三喹烷二烯二酮（9）。

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《Molecules》 |2000年第4期|共页
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Veljko Dragojlovic;
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中图分类有机化学;
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7. Synthesis of a Highly Functionalized Triquinane: Studies Towards a Total Synthesis of Subergorgic Acid and Its Analogues [O] . Veljko Dragojlovic 2013

机译：高功能化Triquinane的合成：subergorgic acid及其类似物的全合成研究

Synthesis of a Highly Functionalized Triquinane: Studies Towards a Total Synthesis of Subergorgic Acid and Its Analogues

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