In 1998, Eric Kandel wrote in his intriguing paper titled “A new intellectual framework for psychiatry” (Kandel, 1998) that “the unique domain which psychiatry occupies within academic medicine, the analysis of the interaction between social and biological determinants of behavior, can best be studied by also having a full understanding of the biological components of behavior.” Fifteen years later, much like surfers who continue a frustrated and longing pursuit for the next “big one” (Cowan et al., 2000; Kandel, 2006), we are, according to Henrik Walter, in the midst of the third wave of biological psychiatry (Walter, 2013). Because a wave is, in a physical sense, a disturbance that propagates through space and time while transferring energy, there are at least three reoccurring “thermodynamic sinks” that I would like to also emphasize with Walter to ultimately better understand the complexity of the human brain in action (Bassett, 2011).
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