50 POSTER Unique enzymatic profile of a potent and selective VEGFR/PDGFR tyrosine kinase inhibitor, TAK-593: potent pseudo-irreversibility against VEGFR and PDGFR

H.Miki; H.Iwata; M.Amamo; S.Imamura; Y.Takagi; A.Hori

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50 POSTER Unique enzymatic profile of a potent and selective VEGFR/PDGFR tyrosine kinase inhibitor, TAK-593: potent pseudo-irreversibility against VEGFR and PDGFR

机译：50 POSTER强效和选择性VEGFR / PDGFR酪氨酸激酶抑制剂TAK-593的独特酶学特征：针对VEGFR和PDGFR的强假不可逆性

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《European Journal of Cancer Supplements》 |2008年第12期|共1页
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H.Miki; H.Iwata; M.Amamo; S.Imamura; Y.Takagi; A.Hori;
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中图分类肿瘤学;
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1. 50 POSTER Unique enzymatic profile of a potent and selective VEGFR/PDGFR tyrosine kinase inhibitor, TAK-593: potent pseudo-irreversibility against VEGFR and PDGFR [J] . H.Miki, H.Iwata, M.Amamo, European Journal of Cancer Supplements . 2008,第12期

机译：50 POSTER强效和选择性VEGFR / PDGFR酪氨酸激酶抑制剂TAK-593的独特酶学特征：针对VEGFR和PDGFR的强假不可逆性
2. 51 POSTER TAK-593, a potent and selective VEGFR/PDGFR tyrosine kinase inhibitor, effects the tumor vascularity and vascular permeability [J] . A.Hori, Y.Kakoi, Y.Takagi, European Journal of Cancer Supplements . 2008,第12期

机译：51 POSTER TAK-593是一种有效的选择性VEGFR / PDGFR酪氨酸激酶抑制剂，可影响肿瘤的血管生长和血管通透性
3. AL3810, a multi-tyrosine kinase inhibitor, exhibits potent anti-angiogenic and anti-tumour activity via targeting VEGFR, FGFR and PDGFR [J] . ZhouY., ChenY., TongL., Journal of cellular and molecular medicine. . 2012,第10期

机译：AL3810是一种多酪氨酸激酶抑制剂，通过靶向VEGFR，FGFR和PDGFR表现出强大的抗血管生成和抗肿瘤活性
4. Taking Quinazoline as a General Support-Nog to Design Potent and Selective Kinase Inhibitors: Application to FMS-like Tyrosine Kinase 3 [C] . Wei-Wei Li, Luo-Ding Yu, Li-Juan Chen, ICMSI;International conference of molecular simulations and applied informatics technologies . 2010

机译：以喹唑啉作为一般支持物来设计有效和选择性激酶抑制剂：在类似FMS的酪氨酸激酶3中的应用
5. Pharmacological Characterization of TAS05567, a Potent and Selective Inhibitor of Spleen Tyrosine Kinase, in Animal Models of Inflammatory Diseases and B-cell Malignancies [D] . 林宏明 2019

机译：TAS05567，脾酪氨酸激酶的强效和选择性抑制剂，在炎症性疾病和B细胞恶性动物模型中的药理特性
6. AL3810 a multi-tyrosine kinase inhibitor exhibits potent anti-angiogenic and anti-tumour activity via targeting VEGFR FGFR and PDGFR [O] . Yuanfeng Zhou, Yi Chen, Linjiang Tong, 2012

机译：多酪氨酸激酶抑制剂AL3810通过靶向VEGFRFGFR和PDGFR表现出有效的抗血管生成和抗肿瘤活性
7. Novel Potent Orally Active Selective VEGFR-2 Tyrosine Kinase Inhibitors: Synthesis, Structure-Activity Relationships, and Antitumor Activities of N-Phenyl-N-{4-(4-quinolyloxy)phenyl}ureas [O] . -1

机译：新型有效口服活性选择性选择性VEGFR-2酪氨酸激酶抑制剂：N-苯基-N- {4-（4-喹啉氧基）苯基}脲的合成，结构活性关系和抗肿瘤活性

50 POSTER Unique enzymatic profile of a potent and selective VEGFR/PDGFR tyrosine kinase inhibitor, TAK-593: potent pseudo-irreversibility against VEGFR and PDGFR

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