首页> 外文OA文献 >Novel Potent Orally Active Selective VEGFR-2 Tyrosine Kinase Inhibitors: Synthesis, Structure-Activity Relationships, and Antitumor Activities of N-Phenyl-N-{4-(4-quinolyloxy)phenyl}ureas

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Novel Potent Orally Active Selective VEGFR-2 Tyrosine Kinase Inhibitors: Synthesis, Structure-Activity Relationships, and Antitumor Activities of N-Phenyl-N-{4-(4-quinolyloxy)phenyl}ureas

机译：新型有效口服活性选择性选择性VEGFR-2酪氨酸激酶抑制剂：N-苯基-N- {4-（4-喹啉氧基）苯基}脲的合成，结构活性关系和抗肿瘤活性

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1. Novel Potent Orally Active Selective VEGFR-2 Tyrosine Kinase Inhibitors:Synthesis,Structure-Activity Relationships,and Antitumor Activities of N-Phenyl-N'-{4-(4-quinolyloxy)phenyl}ureas [J] . Kazuo Kubo, Toshiyuki Shimizu, Shin-ichi Ohyama, Journal of Medicinal Chemistry . 2005,第5期

机译：新型有效的口服活性选择性VEGFR-2酪氨酸激酶抑制剂：N-苯基-N'-{4-（4-喹啉基氧基）苯基}脲的合成，结构-活性关系和抗肿瘤活性
2. A quantitative structure-activity relationship study of novel, potent, orally active, selective VEGFR-2 and PDGFRalpha tyrosine kinase inhibitors: Derivatives of N-Phenyl-N'-{4-(4-quinolyloxy)phenyl}urea as antitumor agents. [J] . Sharma BK, Sharma SK, Singh P, Journal of enzyme inhibition and medicinal chemistry. . 2008,第2期

机译：新型有效的，口服活性的，选择性的VEGFR-2和PDGFRα酪氨酸激酶抑制剂的定量构效关系研究：N-苯基-N'-{4-（4-喹啉基氧基）苯基}脲作为抗肿瘤剂的衍生物。
3. Novel potent orally active multitargeted receptor tyrosine kinase inhibitors: Synthesis, structure-activity relationships, and antitumor activities of 2-indolinone derivatives [J] . Tang P.C., Su Y.D., Feng J., Journal of Medicinal Chemistry . 2010,第22期

机译：新型有效的口服活性多靶受体酪氨酸激酶抑制剂：2-吲哚满酮衍生物的合成，构效关系和抗肿瘤活性
4. Taking Quinazoline as a General Support-Nog to Design Potent and Selective Kinase Inhibitors: Application to FMS-like Tyrosine Kinase 3 [C] . Wei-Wei Li, Luo-Ding Yu, Li-Juan Chen, ICMSI;International conference of molecular simulations and applied informatics technologies . 2010

机译：以喹唑啉作为一般支持物来设计有效和选择性激酶抑制剂：在类似FMS的酪氨酸激酶3中的应用
5. Pharmacological Characterization of TAS05567, a Potent and Selective Inhibitor of Spleen Tyrosine Kinase, in Animal Models of Inflammatory Diseases and B-cell Malignancies [D] . 林宏明 2019

机译：TAS05567，脾酪氨酸激酶的强效和选择性抑制剂，在炎症性疾病和B细胞恶性动物模型中的药理特性
6. 1-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as VEGFR-2 Tyrosine Kinase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modelling Studies [O] . Pedro Soares, Raquel Costa, Hugo J. C. Froufe, 2006

机译：1-芳基-3- [4-（硫代[3,2-d]嘧啶-4-基氧基）苯基]脲作为VEGFR-2酪氨酸激酶抑制剂：合成，生物学评估和分子模型研究
7. Design of new potent and selective secretory phospholipase A2 inhibitors. 6 - Synthesis, structure-activity relationships and molecular modelling of 1-substituted-4-[4,5-dihydro-1,2,4-(4H)-oxadiazol-5-one-3-yl(methyl)]-functionalized aryl piperazin/one/dione derivatives [O] . Meddad-Belhabich, Nadia, Aoun, Darina, Djimdé, Atimé, 2010

机译：新的有效和选择性分泌型磷脂酶A2抑制剂的设计。 6-功能化的1-取代-4- [4,5-二氢-1,2,4-（4H）-恶二唑-5-一-3-基（甲基）]的合成，构效关系和分子模型芳基哌嗪/一/二酮衍生物

Novel Potent Orally Active Selective VEGFR-2 Tyrosine Kinase Inhibitors: Synthesis, Structure-Activity Relationships, and Antitumor Activities of N-Phenyl-N-{4-(4-quinolyloxy)phenyl}ureas

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