1005 High resolution microarray copy number analysis (array CGH) suggests that determination of HER2 amplification by FISH (FISH+) is inaccurate in human breast cancer specimens that are HER2 2+ by immunohistochemistry (IHC2+)

H.L.McArthur; E.Brogi; S.Patil; M.Wigler; L.Norton; J.Hicks; C.A.Hudis

首页> 外文期刊>European Journal of Cancer Supplements >1005 High resolution microarray copy number analysis (array CGH) suggests that determination of HER2 amplification by FISH (FISH+) is inaccurate in human breast cancer specimens that are HER2 2+ by immunohistochemistry (IHC2+)

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1005 High resolution microarray copy number analysis (array CGH) suggests that determination of HER2 amplification by FISH (FISH+) is inaccurate in human breast cancer specimens that are HER2 2+ by immunohistochemistry (IHC2+)

机译：1005高分辨率微阵列拷贝数分析（阵列CGH）表明，通过免疫组织化学（IHC2 +）对人HER2 2+的乳腺癌标本进行FISH（FISH +）的HER2扩增测定是不准确的

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《European Journal of Cancer Supplements》 |2009年第2期|共1页
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H.L.McArthur; E.Brogi; S.Patil; M.Wigler; L.Norton; J.Hicks; C.A.Hudis;
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入库时间 2022-08-18 18:38:58

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1. 1005 High resolution microarray copy number analysis (array CGH) suggests that determination of HER2 amplification by FISH (FISH+) is inaccurate in human breast cancer specimens that are HER2 2+ by immunohistochemistry (IHC2+) [J] . H.L.McArthur, E.Brogi, S.Patil, European Journal of Cancer Supplements . 2009,第2期

机译：1005高分辨率微阵列拷贝数分析（阵列CGH）表明，通过免疫组织化学（IHC2 +）对人HER2 2+的乳腺癌标本进行FISH（FISH +）的HER2扩增测定是不准确的
2. HER2 Gene Copy Number Calculated from Array CGH log2 Signal Intensity Ratios is a Denominator-Stable, High-Resolution Alternative Method for Determining HER2 Status in FISH Equivocal Breast Cancer [J] . Gunn S., Sims C., Govender S., The Journal of molecular diagnostics: JMD . 2016,第6期

机译：从阵列CGH log2信号强度比计算得出的HER2基因拷贝数是一种分母稳定的高分辨率替代方法，用于确定FISH隐性乳腺癌中的HER2状态
3. Impact of HER2 copy number in IHC2+/FISH-amplified breast cancer on outcome of adjuvant trastuzumab treatment in a large UK cancer network [J] . A Borley, T Mercer, M Morgan, British Journal of Cancer . 2014,第8期

机译：英国大型癌症网络中IHC2 + / FISH扩增乳腺癌中HER2拷贝数对曲妥珠单抗辅助治疗结果的影响
4. Automatically diagnosing HER2 amplification status for breast cancer patients using large FISH images [C] . Salar Razavi, Gökhan Hatipoğlu, Hülya Yalçın Signal Processing and Communications Applications Conference . 2017

机译：使用大FISH图像自动诊断乳腺癌患者的HER2扩增状态
5. Breast Cancer With a HER2 IHC2+ and FISH HER2/CEP17 Ratio ≥2.0 and an Average HER2 Gene Copy Number 4.0 per Tumor Cell: HER2 mRNA Overexpression Is a Rare Event [O] . Yuanyuan Liu, Shafei Wu, Xiaohua Shi, 2020

机译：乳腺癌患有HER2 IHC2 +和鱼HER2 / CEP17比率≥2.0和平均HER2基因拷贝数4.0每肿瘤细胞：HER2 mRNA过表达是一个罕见的事件
6. Impact of the 2018 American Society of Clinical Oncology/College of American Pathologists HER2 Guideline Updates on HER2 Assessment in Breast Cancer With Equivocal HER2 Immunohistochemistry Results With Focus on Cases With HER2/CEP17 Ratio 2.0 and Average HER2 Copy Number ≥4.0 and 6.0 [O] . Raza S. Hoda, Edi Brogi, Jin Xu, 2019

机译：2018年美国临床肿瘤学会/美国病理学家学院的影响HER2指南对乳腺癌患者2指南的准则更新，具有等离异性的HER2免疫组化结果，重点关注HER2 / CEP17比例<2.0和平均HER2拷贝数≥4.0和<6.0

1005 High resolution microarray copy number analysis (array CGH) suggests that determination of HER2 amplification by FISH (FISH+) is inaccurate in human breast cancer specimens that are HER2 2+ by immunohistochemistry (IHC2+)

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