Two-Center Evaluation of Disinfectant Efficacy against Ebola Virus in Clinical and Laboratory Matrices

Sophie J. Smither; Lin Eastaugh; Claire Marie Filone; Denise Freeburger; Artemas Herzog; M. Stephen Lever; David M. Miller; Dana Mitzel; James W. Noah; Mary S. Reddick-Elick; Amy Reese; Michael Schuit; Carly B. Wlazlowski; Michael Hevey; Victoria Wahl-Jensen

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Two-Center Evaluation of Disinfectant Efficacy against Ebola Virus in Clinical and Laboratory Matrices

机译：在临床和实验室基质中对埃博拉病毒的消毒效力的两中心评估

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Ebola virus (EBOV) in body fluids poses risk for virus transmission. However, there are limited experimental data for such matrices on the disinfectant efficacy against EBOV. We evaluated the effectiveness of disinfectants against EBOV in blood on surfaces. Only 5% peracetic acid consistently reduced EBOV titers in dried blood to the assay limit of quantification.

机译：体液中的埃博拉病毒（EBOV）构成病毒传播的风险。但是，有关此类基质对EBOV消毒效果的实验数据有限。我们评估了表面血液中消毒剂对EBOV的有效性。仅5％的过乙酸将干血中的EBOV滴度持续降低至测定的定量极限。

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《Emerging Infectious Diseases》 |2018年第1期|共页
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Sophie J. Smither; Lin Eastaugh; Claire Marie Filone; Denise Freeburger; Artemas Herzog; M. Stephen Lever; David M. Miller; Dana Mitzel; James W. Noah; Mary S. Reddick-Elick; Amy Reese; Michael Schuit; Carly B. Wlazlowski; Michael Hevey; Victoria Wahl-Jensen;
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2. Evaluation of Earth Sense Neutral Disinfectant Detergent as an Alternative to Micro-Chem Plus? Detergent Disinfectant for Use in BSL-4 Laboratories using Vesicular Stomatitis Virus as a Surrogate [J] . Sabena Uddowla, Adam Clarkson, Sarah Ziegler, Applied biosafety: Journal of the American Biological Safety Association. . 2016,第1期

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3. Clinical Laboratory Values in Human Ebola Virus Disease Support the Relevance of the Intramuscular Ebola-Kikwit Rhesus Model [J] . Ronald BReisler, Colleen SKraft, SinaBavari, Clinical infectious diseases . 2018,第9期

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5. Molecular cloning, expression, and partial sequencing of the right 45 per cent of the Aleutian disease virus genome and a suspension method to determine reuse life of chemical disinfectants during clinical use. [D] . Robison, Richard A. 1988

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6. Two-Center Evaluation of Disinfectant Efficacy against Ebola Virus in Clinical and Laboratory Matrices [O] . Sophie J. Smither, Lin Eastaugh, Claire Marie Filone, 2018

机译：在临床和实验室基质中对埃博拉病毒的消毒效果的两中心评价
7. Clinical Laboratory Values in Human Ebola Virus Disease Support the Relevance of the Intramuscular Ebola-Kikwit Rhesus Model [O] . Ronald B Reisler, Colleen S Kraft, Sina Bavari, 2017

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Two-Center Evaluation of Disinfectant Efficacy against Ebola Virus in Clinical and Laboratory Matrices

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