Mosquito-associated Dengue Virus, Key West, Florida, USA, 2010

摘要

To the Editor: Except for sporadic cases along the Texas–Mexico border, local transmission of dengue virus (DENV) has not occurred in the contiguous United States since 1946. In 2009, DENV was diagnosed in a vacationer to Key West, Florida (1). Subsequently, 25 other cases were reported that year, transmission was confi rmed by detection of DENV serotype 1 (DENV-1) in local mosquitoes, and a random serosurvey showed evidence of recent DENV infection in 5.4% of Key West residents (1). Transmission continued in 2010, and an additional 63 cases were confi rmed (2). We used PCR amplifi cation and sequence analysis of virus identifi ed from mosquito collections during 2010 to identify the closest relatives, probable geographic origin, and divergence time of the Key West DENV