Human Trypanosoma cruzi Infection and Seropositivity in Dogs, Mexico

摘要

We used 5 diagnostic tests in a cross-sectional inves-tigation of the prevalence of Trypanosoma cruzi in Tejupilcomunicipality, State of Mexico, Mexico. Our findings showeda substantial prevalence of immunoglobulin G (IgG) andIgM antibodies to T. cruzi in human (n = 293, IgG 2.05%,IgM 5.5%, both 7.1%) and dog (n = 114, IgG 15.8%, IgM11.4%, both 21%) populations. We also found antibodies toT. cruzi (n = 80, IgG 10%, IgM 15%, both 17.5%) in dogsfrom Toluca, an area previously considered free of T. cruzi.Our data demonstrate the need for active epidemiologicsurveillance programs in these regions. A direct correlation(r2 = 0.955) of seropositivity between humans and dogssuggests that seroanalysis in dogs may help identify thehuman prevalence of T. cruzi infection in these areas