Evolution of Seventh Cholera Pandemic and Origin of 1991 Epidemic, Latin America

摘要

Thirty single-nucleotide polymorphisms were used to track the spread of the seventh pandemic caused by Vibrio cholerae. Isolates from the 1991 epidemic in Latin America shared a profi le with 1970s isolates from Africa, suggesting a possible origin in Africa. Data also showed that the ob-served genotypes spread easily and widely