Rapid Increase in Carriage Rates of Enterobacteriaceae Producing Extended-Spectrum β-Lactamases in Healthy Preschool Children, Sweden

摘要

By collecting and analyzing diapers, we identified a 6-fold increase in carriage of extended-spectrum β-lactamase (ESBL)–producing Enterobacteriaceae for healthy preschool children in Sweden (p 40%. We analyzed samples from 334 children and found 56 containing 1 ESBL producer. The prevalence in the study population increased from 2.6% in 2010 to 16.8% in 2016 (p 40%. Furthermore, 58% of the ESBL producers were multidrug resistant, and transmission of ESBL-producing and non–ESBL-producing strains was observed at several of the preschools. Toddlers appear to be major carriers of ESBL producers in Sweden.