937 Superiority of aprepitant, an oral NK1 antagonist, over standard antiemetic therapy: Reducing the impact of nausea and vomiting on patients' daily lives

A.R.Martin; G.J.Ma; A.D.Carides; K.Horgan; F.Lawson; M.Elmer; C.Schmidt; C.M.Lindley; M.Aapro

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937 Superiority of aprepitant, an oral NK1 antagonist, over standard antiemetic therapy: Reducing the impact of nausea and vomiting on patients' daily lives

机译：937口服NK1拮抗剂aprepitant优于标准止吐疗法：减少恶心和呕吐对患者日常生活的影响

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《European Journal of Cancer Supplements》 |2003年第5期|共1页
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A.R.Martin; G.J.Ma; A.D.Carides; K.Horgan; F.Lawson; M.Elmer; C.Schmidt; C.M.Lindley; M.Aapro;
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中图分类肿瘤学;
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1. 937 Superiority of aprepitant, an oral NK1 antagonist, over standard antiemetic therapy: Reducing the impact of nausea and vomiting on patients' daily lives [J] . A.R.Martin, G.J.Ma, A.D.Carides, European Journal of Cancer Supplements . 2003,第5期

机译：937口服NK1拮抗剂aprepitant优于标准止吐疗法：减少恶心和呕吐对患者日常生活的影响
2. Addition of the oral NK1 antagonist aprepitant to standard antiemetics provides protection against nausea and vomiting during multiple cycles of cisplatin-based chemotherapy. [J] . de Wit R, Herrstedt J, Rapoport B, Journal of Clinical Oncology . 2003,第22期

机译：在标准的止吐药中添加口服NK1拮抗剂aprepitant可在基于顺铂的化学疗法的多个周期中提供防止恶心和呕吐的保护作用。
3. Aprepitant: an oral NK1 antagonist for the prevention of nausea and vomiting induced by highly emetogenic chemotherapy. [J] . Pendergrass K, Hargreaves R, Petty KJ, Drugs of today: Medicamentos de actualidad . 2004,第10期

机译：Aprepitant：一种口服NK1拮抗剂，用于预防因高度致呕的化学疗法引起的恶心和呕吐。
4. Hollow silicon microneedle array based trans-epidermal antiemetic patch for efficient management of Chemotherapy Induced Nausea and Vomiting [C] . Bhushan N Kharbikar, Harish Kumar S, Sindhu Kr, Micro+nano materials, devices, and systems . 2015

机译：基于中空硅微针阵列的经表皮止吐贴剂可有效管理化学疗法诱发的恶心和呕吐
5. The effectiveness of a preoperative multimodal antiemetic regimen on reducing early postoperative nausea and vomiting in total joint arthroplasty patients [D] . Mosley, Jerry, Jr. 2015

机译：术前多模式止吐方案对减少全关节置换患者术后早期恶心和呕吐的有效性
6. Efficacy of triple antiemetic therapy (palonosetron dexamethasone aprepitant) for chemotherapy-induced nausea and vomiting in patients receiving carboplatin-based moderately emetogenic chemotherapy [O] . Toshimichi Miya, Kunihiko Kobayashi, Mitsunori Hino, -1

机译：三联止吐疗法（帕洛诺司琼地塞米松阿瑞吡坦）在接受以卡铂为基础的中度致呕性化疗的患者中对化疗引起的恶心和呕吐的疗效
7. Chemotherapy is one of the therapies for cancer patients that cause some side effects, one of them is nausea and vomiting. Nausea and vomiting are still felt by patients even though they take antiemetics. Nausea dan vomiting can cause fluid and electrolyte imbalance. The aim of this study was to analysis the effect of combination acupressure wristband and antiemetic among chemotherapy induced nausea vomiting (CINV) on breast cancer patients. This research used quasi experimental research method, with a pre-post test with the control group. The sampling techniques was consecutive sampling with 25 respondents both in intervention group and control group. In the intervention group had received an acupressure wristband. CINV measured on the second day until fourth day after chemotherapy. Nausea and vomiting score were measured twice a day by a telemonitoring methode by Rhodes Index Nausea, Vomiting and Retching (INVR) questionaire. Data were analyzed by paired t-test, independent t-test, Wilcoxon test and Mann Whitney. The result of this study showed that acupressure wristband significantly reduce the chemotherapy induced nausea and vomit (p value = 0.000). The use of acupressure wristband combined with antiemetic therapy can significantly decrease chemotherapy induced nausea and vomiting in breast cancer patients. Acupressure wristband recommended for consideration nursing intervention in treating breast cancer patients who experience nausea and vomiting. [O] . Endah Fatma 2018

机译：化疗是癌症患者的疗法之一，导致一些副作用，其中一个是恶心和呕吐。患者仍然感受到恶心和呕吐，即使他们服用助性学。恶心丹呕吐会导致液体和电解质不平衡。本研究的目的是分析组合组合腕带和抑制在乳腺癌患者中的诱导恶心呕吐（CINV）的影响。本研究使用了准实验研究方法，用对照组进行了预先测试。采样技术是在干预组和对照组中进行25名受访者的连续抽样。在干预组中，收到了一名腕带。 Cinv在化疗后第四天测量。通过罗得岛指数恶心，呕吐和转换（INVR）问卷，每天测量恶心和呕吐分数。通过配对的T检验，独立的T检验，Wilcoxon测试和Mann Whitney分析数据。该研究的结果表明，Acuruce腕带显着降低化疗诱导的恶心和呕吐物（P值= 0.000）。使用Acu压抑腕带与止吐疗法相结合，可以显着降低乳腺癌患者诱导的恶心和呕吐。 Acu压痕腕带推荐用于治疗体验恶心和呕吐的乳腺癌患者的护理干预。

937 Superiority of aprepitant, an oral NK1 antagonist, over standard antiemetic therapy: Reducing the impact of nausea and vomiting on patients' daily lives

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