Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis (http://wwwnc.cdc.gov/eid/article/21/1/14-0790)

摘要

Treponema pallidum PCR ( Tp- PCR) has been noted as a valid method for diagnosing syphilis. We compared Tp- PCR to a combination of darkfield microscopy (DFM), the reference method, and serologic testing in a cohort of 273 patients from France and Switzerland and found the diagnostic accuracy of Tp- PCR was higher than that for DFM.