Cryptococcus meningitis and the genotypes of cryptococcus neoformans prevalent in Western Maharashtra, India

摘要

Background: Cryptococcal meningitis is an AIDs defining illness. However the disease is seen in patients without HIV infection also. Attempts have been made to develop a vaccine for the disease, so the prevalent genotypes of Cryptococcal neoformans need to be identified. In the Indian scenario there is a paucity of literature on MLST genotyping. Genotyping of C. neoformans can be performed for epidemiological purpose, to determine whether the cryptococcosis is caused by single genotype or two or more genotypes and to develop vaccine production.