Genotyping of mycobacterium tuberculosis strains isolated from patients with pulmonary drug resistant tuberculosis in Ukraine

摘要

Background: The epidemiological situation of tuberculosis in Ukraine is extremely unfavorable – about 40 thousand people become sick on tuberculosis each year and about 10 thousand patients die. Changing of the contemporary socio-economic and environmental conditions plays an important role in the deterioration of the tuberculosis epidemic situation. Moreover drug resistance of M.tuberculosis is one of the main factors limiting the effectiveness of TB treatment. Due to the development of molecular genetics it has become possible to conduct genetic typing of bacteria, which allows distinguishing between different strains of the pathogen isolated from TB patients.