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Anti-Fatigue Properties of Tartary Buckwheat Extracts in Mice

机译:苦荞提取物对小鼠的抗疲劳特性

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Anti-fatigue properties of tartary buckwheat extracts (TBE) was investigated in male Kunming mice. The animals were divided into four groups. The first group, designated as the control group (control), was administered with distilled water by gavage every day for 28 days. The other three groups, designated as TBE treatment groups, were administered with TBE of 60, 120 and 240 mg/kg body weight, respectively, by gavage every day for 28 days. Exhaustive swimming time, blood lactic acid (BLA), blood urea nitrogen (BUN), tissue glycogen, glutathione peroxidase (GPx) and superoxide dismutase (SOD) of mice after swimming were determined. The results showed that tartary buckwheat extracts had anti-fatigue properties, which extended the exhaustive swimming time of mice, effectively inhibiting the increase of BLA, decreasing the level of BUN, increasing the tissue glycogen content and the activities of SOD and GPx of mice. However, further study is needed to elucidate the exact mechanism of the effect of TBE on fatigue.
机译:在雄性昆明小鼠中研究了苦荞提取物(TBE)的抗疲劳特性。将动物分为四组。第一组,称为对照组(对照组),每天用管饲法蒸馏水28天。其余三组被指定为TBE治疗组,分别通过管饲法每天分别给予60、120和240 mg / kg体重的TBE,持续28天。测定了游泳后小鼠的力竭游泳时间,血乳酸(BLA),血尿素氮(BUN),组织糖原,谷胱甘肽过氧化物酶(GPx)和超氧化物歧化酶(SOD)。结果表明,苦荞提取物具有抗疲劳特性,延长了小鼠的力竭游泳时间,有效抑制了小鼠BLA的升高,降低了BUN的水平,增加了小鼠的组织糖原含量以及SOD和GPx的活性。然而,需要进一步的研究来阐明TBE对疲劳的影响的确切机制。

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