Knowledge, attitudes and practices regarding hantavirus disease and willingness to participate in a hantavirus vaccine trial in southern Chile

摘要

Background: Hantavirus disease (HD) in Chile is caused by Andes virus with mortality rate of 35% and no specific treatment. State-of-the-art research in hantavirus vaccines (HV) allow envisioning candidate Andes vaccines in the near future. This vaccine/s will need Phase II evaluation in people at highest risk of infection, such as rural inhabitants. We aimed to assess knowledge of HD and willingness to participate in a future HV trial in two rural locations in southern Chile.