Clinical Impact and Current Epidemiology of Carbapenemase producers

摘要

Carbapenemase-producing pathogens have become a major and increasing infectious disease threat. Their most serious impact is the lack effective therapies for the infections they cause. Given that laboratory detection is often poor, our understanding of their epidemiology is incomplete. Some types of carbapenemase producers are already ubiquitous. For other types, there are known hotspots of occurrence. KPC producers are mostly detected in the eastern USA and Israel, but have also been detected in some European and Asian countries.