Rate of decline of antibody titres to influenza A/California/7/2009 (H1N1) by haemagglutination inhibition and virus neutralization assays in a cohort of seroconverting adults in Singapore

摘要

Background: The rate of decline of antibody titres to influenza following infection can affect results from sero-surveys, and population level decline in such titres may explain the pattern of repeat epidemics observed in pdmH1N1 influenza A. We describe changes in antibody titres in a cohort of adults who seroconverted during the initial wave of pdmH1N1 infections in Singapore.