Longitudinal molecular epidemiological study of multidrug resistant TB and transition to extensively drug resistance in eastern rual China

摘要

Background: Continuous understanding of the epidemiology and evolution of multidrug resistant TB (MDR-TB) is key to develop the appropriate strategies for preventing its epidemic. The present study aimed to investigate the longitudinal trend of its rates, transmissions and transition to extensively drug resistant TB(XDR-TB), in an attempt to adjust the TB control activities in eastern rural China.