Concurrent infection of different dengue virus serotypes in fatal cases during an outbreak in Colombia, 2010

摘要

Background: Dengue virus (DENV) is an arthropod borne flavivirus responsible of a major viral re-emergent disease in tropical and sub-tropical countries, affecting about 50 million people at year around the world. In Colombia dengue outbreaks occurs every five or six year, but the infection is endemic and constantly reported in most of the country. During the last year, Colombia went through the largest dengue epidemic occurred in decades, with 157.152 cases notified, 217 deaths confirmed and all four viral serotypes co-circulating.