Development of Serodiagnostic Method for the Detection of Serotype-Specific Anti-Coxsackievirus Antibodies

摘要

Coxsackieviruses (CV) are associated with several clinical manifestations ranging from mild upper respiratory infections to meningitis and myocarditis. Different serotypes have been implicated in the appearance of different manifestations. Nowadays, virus identification depends on virus isolation and cultivation and the use of neutralization tests. In this study, we developed an Enzyme-Linked Immunosorbent Assay (ELISA) with the ability to discriminate among different serotypes of Coxsackie viruses.