Trends in Methicillin resistant staphylococcus aureus (MRSA) minimal inhibitory concentration (MIC) to Vancomycin over a 2 year period in a community based hospital

摘要

Background: Clinical and laboratory standards institute (CLSI) susceptible range for MRSA isolates to Vancomycin is established at MIC of 2mcg/ml or less, however MRSA isolates with higher MIC within the susceptible range are being reported more frequently. It has been reported that the clinical response to therapy with vancomycin for patients infected with MRSA isolates with MIC's ≥ 1.5 to 2?mcg/ml is decreased.