Cryptococcal meningitis in a patient treated with infliximab and mycophenolate mofetil for Behcet's disease

摘要

A 46-year-old Caucasian male was admitted in June 2007 for a recent history of headaches and fever. He had been treated for Beh?et's disease for the past seven years, with recurrent oral aphtosis, diffuse arthralgias and severe uveitis. Unusual severe bilateral uveitis prompted us to give oral corticosteroids for 30 months, infliximab for 18 months and mycophenolate mofetil (2?g/day) for 14 months. Infliximab was started in January 2006 at a dose of 3?mg/kg/infusion (250?mg) and then 5?mg/kg/infusion (400?mg) in January 2007.