Quantitative Study of Structure-Activity Relationship (Q.S.A.R.) of Antimalarial Compounds Isolated from Solanum nudum and Derivatives Synthesis

摘要

Malaria is the main parasitic desease, responsible for more than 300 million cases and more than two million annual dead, causing major human and economic losses. In addition, there are more than 2,400 million people at risk of contracting this infection according to a report of the Pan American Health Organization (PAHO). Colombia presents 195.719 cases of malaria. New alternatives for treatment of malaria are needed and one is searching new drugs from natural products.