Lack of Association of Interleukin-8 Gene Polymorphism with Helicobacter pylori-Induced Gastritis in Iranian Patients

摘要

Background: Helicobacter pylori is a major cause of neoplastic and inflammatory gastroduodenal diseases of the stomach. Recently cytokine gene polymorphisms and H. pylori have been linked to different gastric diseases. In this study we determined the role of host Interleukin-8 (?251A/T) gene polymorphism in the development of gastritis in the population of southern Iran.