In-Silico Studies of Halophilic Archaeon DL31 Plasmids for Gene Annotation and Structure Prediction

摘要

The Insilico structure prediction, gene annotation and sub-cellular location were determined for the hypothetical proteins in two plasmids from U nclassified Halophilic archaeon DL31 plasmids. The probable structures were predicted for 92 hypothetical proteins by the use of PS2structure prediction server. The functional an notation for 68 proteins was possible by the use of Bioinformatics web tools like CDD -Blast, Interproscan and pfam by searching the presence of conserved domains amongst the different kno wn proteins and their families through online databases. The Sub-cellular location predictions were done for all the 92 unclassified hypothetical proteins by using CELLO v 2.5 servers. Through comparative geno mics approach t his study revealed vario us functional hypothetical proteins in two plasmids of Unclassified Halophilic archaeon DL31