Local and Systemic Immune Responses to Rectal Administration of Recombinant Cholera Toxin B Subunit in Humans

Marianne Jertborn; Inger Nordstr?m; Anders Kilander; Cecil Czerkinsky; Jan Holmgren

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Local and Systemic Immune Responses to Rectal Administration of Recombinant Cholera Toxin B Subunit in Humans

机译：直肠和人体内重组霍乱毒素B亚基对直肠给药的局部和全身免疫应答

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The induction of immune responses to rectally administered recombinant cholera toxin B subunit (CTB) in humans was studied. Three immunizations induced high levels of CTB-specific antibody-secreting cells, particular of the immunoglobulin A isotype, in both rectum and peripheral blood. Antitoxin antibody responses in rectal secretions and serum were also found.

机译：研究了对人中经直肠施用的重组霍乱毒素B亚基（CTB）的免疫应答诱导作用。三种免疫均在直肠和外周血中诱导高水平的CTB特异性抗体分泌细胞，特别是免疫球蛋白A同种型。还发现了直肠分泌物和血清中的抗毒素抗体反应。

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《Infection and immunity》 |2001年第6期|共4页
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Marianne Jertborn; Inger Nordstr?m; Anders Kilander; Cecil Czerkinsky; Jan Holmgren;
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中图分类医学免疫学;
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1. Kinetics of Local and Systemic Immune Responses after Vaginal Immunization with Recombinant Cholera Toxin B Subunit in Humans [J] . Lotta Wassen, Marianne Jertborn Clinical and diagnostic laboratory immunology . 2005,第3期

机译：重组霍乱毒素B亚单位的阴道免疫后人体的局部和全身免疫反应的动力学。
2. Intranasal vaccination of humans with recombinant cholera toxin B subunit induces systemic and local antibody responses in the upper respiratory tract and the vagina. [J] . C Bergquist, E L Johansson, T Lagerg?rd, Infection and immunity . 1997,第7期

机译：用重组霍乱毒素B亚单位对人进行鼻内疫苗接种可在上呼吸道和阴道中诱导全身和局部抗体反应。
3. Intranasal vaccination of humans with recombinant cholera toxin B subunit induces systemic and local antibody responses in the upper respiratory tract and the vagina. [J] . C Bergquist, E L Johansson, T Lagerg?rd, Infection and immunity . 1997,第7期

机译：用重组霍乱毒素B亚单位对人进行鼻内疫苗接种可在上呼吸道和阴道中诱导全身和局部抗体反应。
4. Dynamic Modeling of Binding Kinetics Between GD1b Ganglioside and Cholera Toxin Subunit B [C] . Dongheon Lee, Akshi Singla, Hung-Jen Wu, 2018 Annual American Control Conference . 2018

机译：GD1b神经节苷脂和霍乱毒素亚基B结合动力学的动力学模型
5. Cholera Toxin B Subunit-Diabetes Autoantigen Fusion Proteins Modulate Dendritic Cell Function and T Cell Morphogenesis [D] . Odumosu, Oludare Jerremiah 2011

机译：霍乱毒素B亚基-糖尿病自身抗原融合蛋白调节树突状细胞功能和T细胞形态发生。
6. Note: Local and Systemic Immune Responses to Rectal Administration of Recombinant Cholera Toxin B Subunit in Humans [O] . Marianne Jertborn, Inger Nordström, Anders Kilander, 2001

机译：注意：人类对重组霍乱毒素B亚基直肠给药的局部和全身免疫反应
7. Local and Systemic Immune Responses to Rectal Administration of Recombinant Cholera Toxin B Subunit in Humans [O] . Jertborn, Marianne, Nordström, Inger, Kilander, Anders, 2001

机译：人体对重组霍乱毒素B亚基直肠给药的局部和全身免疫反应。
8. Purification and Analysis of a Recombinant Human Anti-Cholera Toxin B Antibody [R] . Dang, J., Kracke, S., Emanuel, P. A., 1998

机译：重组人抗霍乱毒素B抗体的纯化与分析

Local and Systemic Immune Responses to Rectal Administration of Recombinant Cholera Toxin B Subunit in Humans

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