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Are Heptodes Better than Tetrodes for Spike Sorting?

机译:在穗分类方面,七极比四极好吗?

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Multi-neuron extracellular recordings with multichannel microelectrodes, like tetrodes or heptodes, are used to get insights in the neuronal information processing in the brain. Spike sorting is the detection and classification of extracellular action potentials (spikes) recorded with these electrodes. Here we report on the improvement of spike sorting performance when using heptodes rather than tetrodes by simulating tetrode/heptode recordings and analysing them automatically with our spike sorting algorithm. Simulation of signals is performed via a simple model of neurons and electrodes that has the ability to emulate preferably realistic recording conditions without too much complexity. Results indicate that spike sorting performance is better when heptodes instead of tetrodes are used to record from highly active local clusters consisting of many neurons and when the signals have a low signal-to-noise ratio.
机译:具有多通道微电极(如四极或七极)的多神经元细胞外记录可用于洞悉大脑中神经元信息的过程。尖峰分类是通过这些电极记录的细胞外动作电位(尖峰)的检测和分类。在这里,我们通过模拟四极体/七极体记录并使用我们的尖峰分类算法自动分析它们,来报告使用七极体而不是四极体时尖峰分类性能的改进。信号的模拟是通过神经元和电极的简单模型执行的,该模型具有模拟真实记录条件的能力,而不会过于复杂。结果表明,当使用七极体而不是四极体来记录由许多神经元组成的高度活跃的局部簇并且信号的信噪比较低时,尖峰排序性能会更好。

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