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Teichoic Acid Glycosylation Mediated by gtcA Is Required for Phage Adsorption and Susceptibility of Listeria monocytogenes Serotype 4b

机译:gtcA介导的Teichoic酸糖基化是噬菌体吸附和单核细胞增生性李斯特菌血清型4b敏感性的必需条件

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摘要

An insertion mutant of gtcA, responsible for serotype-specific glycosylation of the cell wall teichoic acid in serotype 4b strains of Listeria monocytogenes, was also resistant to both Listeria genus- and serotype 4b-specific phages. The sugar substituents on teichoic acid appeared essential for the adsorption of phages A500 (serotype 4b specific) and A511 (Listeria genus specific) to serotype 4b L. monocytogenes.
机译:负责单核细胞增生李斯特菌血清型4b菌株中细胞壁甲壁酸血清型特异性糖基化的gtcA插入突变体也对李斯特菌属和血清型4b特异性噬菌体具有抗性。硫磷酸上的糖取代基看来对于将噬菌体A500(血清型4b特异性)和A511(李斯特菌属特异性)吸附至血清型4b单核细胞增生李斯特菌至关重要。

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