Genetic Analysis of Two Bile Salt Hydrolase Activities in Lactobacillus acidophilus NCFM

Olivia McAuliffe; Raul J. Cano; Todd R. Klaenhammer

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Genetic Analysis of Two Bile Salt Hydrolase Activities in Lactobacillus acidophilus NCFM

机译：嗜酸乳杆菌NCFM中两种胆汁盐水解酶活性的遗传分析

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Two genes, bshA and bshB, encoding bile salt hydrolase enzymes (EC 3.5.1.24) were identified in the genome sequence of Lactobacillus acidophilus NCFM. Targeted inactivation of these genes via chromosomal insertion of an integration vector demonstrated different substrate specificities for these two enzymes.

机译：在嗜酸乳杆菌NCFM的基因组序列中鉴定出两个编码胆汁盐水解酶的基因bshA和bshB（EC 3.5.1.24）。通过整合载体的染色体插入使这些基因靶向失活，表明这两种酶具有不同的底物特异性。

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《Applied and Environmental Microbiology》 |2005年第8期|共5页
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Olivia McAuliffe; Raul J. Cano; Todd R. Klaenhammer;
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1. Effect of Bile Salt Hydrolase Inhibitors on a Bile Salt Hydrolase from Lactobacillus acidophilus [J] . Guolong Zhang, Jun Lin, Katie Smith, Pathogens . 2014,第4期

机译：胆汁盐水解酶抑制剂对嗜酸乳杆菌胆汁盐水解酶的影响
2. Isolation and characterization of a Lactobacillus amylovorus mutant depleted in conjugated bile salt hydrolase activity: relation between activity and bile salt resistance [J] . J.P. Grill, C. Cayuela, J.M. Antoine, Journal of applied microbiology . 2000,第4期

机译：耗竭的共轭胆盐水解酶活性中耗竭的嗜淀粉乳杆菌突变体的分离和鉴定：活性与胆盐抗性之间的关系
3. Molecular Cloning and Characterization of a Bile Salt Hydrolase from Lactobacillus acidophilus PF01 [J] . Oh Hae-Keun, Ji Yoon Lee, Soo Jin Lim, Journal of microbiology and biotechnology . 2008,第3期

机译：嗜酸乳杆菌PF01胆汁盐水解酶的分子克隆与表征
4. Studies on the Action mechanism for Cholesterol-lowering of Lactobacillus which yields Bile Salt Hydrolase from Kefir Grains [C] . Hui Liu, Yuanhong Xie, Tao Han, International Conference on Chemical Engineering and Advanced Materials . 2013

机译：乳酸乳杆菌胆固醇降低的作用机制研究，其产生胆汁盐水解酶
5. Influence ofpH on bile salt deconjugation and removal of cholesterol from media by Lactobacillus casei and Lactobacillus acidophilus during growth [D] . Brashears, Mindy Malynn 1997

机译：pH对干酪乳杆菌和嗜酸乳杆菌生长过程中胆汁盐解偶联和胆固醇从培养基中去除的影响
6. Genetic Analysis of Two Bile Salt Hydrolase Activities in Lactobacillus acidophilus NCFM [O] . Olivia McAuliffe, Raul J. Cano, Todd R. Klaenhammer 2005

机译：嗜酸乳杆菌NCFM中两种胆汁盐水解酶活性的遗传分析
7. Genetic Analysis of Two Bile Salt Hydrolase Activities in Lactobacillus acidophilus NCFM [O] . McAuliffe, Olivia, Cano, Raul J., Klaenhammer, Todd R. 2005

机译：嗜酸乳杆菌NCFM中两种胆汁盐水解酶活性的遗传分析

Genetic Analysis of Two Bile Salt Hydrolase Activities in Lactobacillus acidophilus NCFM

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