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Pulmonary ultrasound and pulse oximetry versus chest radiography and arterial blood gas analysis for the diagnosis of acute respiratory distress syndrome: a pilot study

机译:肺部超声和脉搏血氧饱和度测定法与胸部放射线照相和动脉血气分析在诊断急性呼吸窘迫综合征中的初步研究

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IntroductionIn low-resource settings it is not always possible to acquire the information required to diagnose acute respiratory distress syndrome (ARDS). Ultrasound and pulse oximetry, however, may be available in these settings. This study was designed to test whether pulmonary ultrasound and pulse oximetry could be used in place of traditional radiographic and oxygenation evaluation for ARDS.MethodsThis study was a prospective, single-center study in the ICU of Harborview Medical Center, a referral hospital in Seattle, Washington, USA. Bedside pulmonary ultrasound was performed on ICU patients receiving invasive mechanical ventilation. Pulse oximetric oxygen saturation (SpO2), partial pressure of oxygen (PaO2), fraction of inspired oxygen (FiO2), provider diagnoses, and chest radiograph closest to time of ultrasound were recorded or interpreted.ResultsOne hundred and twenty three ultrasound assessments were performed on 77 consecutively enrolled patients with respiratory failure. Oxygenation and radiographic criteria for ARDS were met in 35 assessments. Where SpO2?≤?97?%, the Spearman rank correlation coefficient between SpO2/FiO2 and PaO2/FiO2 was 0.83, p?
机译:简介在资源贫乏的地区,并非总是能够获得诊断急性呼吸窘迫综合征(ARDS)所需的信息。但是,在这些设置中可能会使用超声和脉搏血氧饱和度测定法。本研究旨在测试是否可以使用肺部超声和脉搏血氧饱和度测定法代替ARDS的传统放射线照相和氧合评估方法。美国华盛顿。对接受有创机械通气的ICU患者进行床旁肺部超声检查。记录或解释脉搏血氧饱和度(SpO2),氧分压(PaO2),吸氧分数(FiO2),提供者诊断以及最接近超声时间的胸部X线照片。结果对120例超声进行了评估连续入选呼吸衰竭的患者77例。 35次评估符合ARDS的氧合和放射照相标准。当SpO2≤≤97%时,SpO2 / FiO2和PaO2 / FiO2之间的Spearman等级相关系数为0.83,p≤<0.0001。先前报道的SpO2 /FiO2≤≤300的SpO2 /FiO2≤≤315阈值的敏感性和特异性分别为83%(95%置信区间(CI)68-93)和50%(95%)。 %CI 1–99)。 PaO2 /FiO2≤≤200的SpO2 /FiO2≤≤235的灵敏度和特异性分别为70%(95%CI 47-87)和90%(95%CI 68-99)。对于研究医师解释的肺部超声评估,双向超声间质综合征的敏感性和特异性分别为80%(95%CI 63-92)和62%(95%CI 49-92)。 74)。将SpO2 / FiO2与超声结合以确定ARDS的氧合和放射学标准,其敏感性为83%(95%CI 52-98),特异性为62%(95%CI 38-82)。对于中度至重度ARDS标准(PaO2 /FiO2≤200),敏感性为64%(95%CI 31-89),特异性为86%(95%CI 65-97)。排除重复评估和对超声图像的独立解释不会明显改变敏感性指标。结论脉搏血氧饱和度测定法和肺超声检查可能是筛查或排除在资源贫乏地区动脉血中与ARDS相一致的氧合受损或肺部异常的有用工具电子补充材料本文的在线版本(doi:10.1186 / s13054-015-0995-5)包含补充材料,授权用户可以使用。

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