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Six-month quality-of-life and functional status of acute respiratory distress syndrome survivors compared to patients at risk: a population-based study

机译:一项基于人群的研究与急性高危患者相比,急性呼吸窘迫综合征幸存者的六个月生活质量和功能状态

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IntroductionThe long-term attributable burden related to acute respiratory distress syndrome (ARDS) is not fully investigated. The aim of this study is to evaluate the quality of life (QOL) and functional status at 6?months after hospitalization in patients at risk for ARDS who did and did not develop the syndrome.MethodThis is a population-based prospective cohort study of adult patients from Olmsted County, Minnesota, with or at risk for ARDS hospitalized from October 2008 to July 2011. The primary outcomes were changes in QOL and functional status, measured through 12-Item Short Form Survey (SF-12) and Barthel Index (BI) respectively, from baseline to 6?months, compared between survivors who did and did not develop ARDS.ResultsOf 410 patients with or at risk for ARDS, 98 had baseline surveys collected and 67 responded to a 6-month survey (26 ARDS, 41 non-ARDS). Both ARDS and non-ARDS groups had lower physical component of SF-12 at baseline compared to general population (P?
机译:简介尚未完全调查与急性呼吸窘迫综合征(ARDS)相关的长期可归因负担。这项研究的目的是评估在住院后6个月有和没有发展为综合症的ARDS高危患者的生活质量(QOL)和功能状态。方法这是一项基于人群的成人前瞻性队列研究明尼苏达州Olmsted县的患有ARDS或有ARDS风险的患者于2008年10月至2011年7月住院。主要结果是QOL和功能状态的变化,通过12项简短表格调查(SF-12)和Barthel指数(BI)进行测量),从基线到6个月分别比较有和没有发展ARDS的幸存者。结果在410名有ARDS或有ARDS风险的患者中,收集了98份基线调查,有67份对6个月调查做出了回应(26 ARDS,41非ARDS)。与普通人群相比,ARDS组和非ARDS组在基线时的SF-12物理成分均较低(两者的P 0.001)。与非ARDS相比,ARDS患者的基线功能状态较差(BI平均为80±±25 vs. 88±±22,P≥0.03)。在6个月和基线BI之间的变化(ARDS的差异为2.3,非ARDS的差异为2.0,P≥0.5)或精神方面(差异2.7与2.4,差异P≤0.9)没有观察到显着差异。或没有ARDS的幸存者之间SF-12的物理或物理(δ–3与–3.3,P?=?0.9)(δ–3 vs.3.3)。结论在这项基于人群的研究中,住院后6个月的QOL和功能状态下降主要由以下因素解释:基线状况,有和没有发展ARDS的幸存者的恢复情况相似。电子补充材料本文的在线版本(doi:10.1186 / s13054-015-1062-y)包含补充材料,授权用户可以使用。

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