首页> 外文期刊>Clinical Chemistry: Journal of the American Association for Clinical Chemists >Estimation of thyroxin, triiodothyronine, thyrotropin, free thyroxin, and triiodothyronine uptake by use of magnetic-particle solid phases.
【24h】

Estimation of thyroxin, triiodothyronine, thyrotropin, free thyroxin, and triiodothyronine uptake by use of magnetic-particle solid phases.

机译:通过使用磁性粒子固相估算甲状腺素,三碘甲状腺素,促甲状腺素,游离甲状腺素和三碘甲状腺素的摄取。

获取原文
获取外文期刊封面目录资料

摘要

We evaluated solid-phase radioassays involving small, uniform magnetic particles (MAGIC, Corning Medical), obtaining data on total serum thyroxin (T4), triiodothyronine (T3), thyrotropin (TSH), free thyroxin (FT4), and T3 uptake for a total of 301 serum samples from euthyroid patients; patients receiving replacement thyroxin; patients receiving estrogen, or who were pregnant; hyperthyroid, hypothyroid, and nonthyroidally ill patients; and patients receiving salicylates, phenytoin, or heparin. We found each procedure to be technically simple and precise (between-assay CVs for T4 2.8-8.2%, T3 9-7.4%, TSH 2.9-4.5%, FT4 3.6-11%, T3 uptake 2.2-3.7%). The magnetic separations are rapid (2 to 5 min), reproducible, and complete. Each MAGIC assay produced clinically appropriate results. These assay systems offer the convenience associated with noncentrifugation assays and excellent analytical performance.
机译:我们评估了涉及小的均匀磁性颗粒(MAGIC,康宁医学公司)的固相放射分析方法,获得了血清总甲状腺素(T4),三碘甲状腺素(T3),促甲状腺激素(TSH),游离甲状腺素(FT4)和T3摄取的数据共有301例甲状腺疾病患者的血清样本;接受替代甲状腺素的患者;接受雌激素或怀孕的患者;甲状腺功能亢进,甲状腺功能减退和非甲状腺疾病的患者;以及接受水杨酸盐,苯妥英钠或肝素的患者。我们发现每种方法在技术上都很简单准确(T4介于2.8-8.2%,T3介于9-7.4%,TSH 2.9-4.5%,FT4 3.6-11%,T3吸收2.2-3.7%的测定间CV)。磁分离速度快(2至5分钟),可重复且完全。每种MAGIC分析均产生临床上适当的结果。这些测定系统提供了非离心测定的便利性和出色的分析性能。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号