Comprehensive analysis of copy number aberrations in microsatellite stable colon cancer in view of stromal component

M HenarAlonso; SusannaAussó; AdrianaLopez-Doriga; DavidCordero; ElisabetGuinó; XavierSolé; MercèBarenys; Javierde Oca; GabrielCapella; RamónSalazar; RebecaSanz-Pamplona; and VictorMoreno

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Comprehensive analysis of copy number aberrations in microsatellite stable colon cancer in view of stromal component

机译：基于基质成分的微卫星稳定结肠癌拷贝数畸变综合分析

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Background:Somatic copy number aberrations (CNAs) are common acquired changes in cancer cells having an important role in the progression of colon cancer (colorectal cancer, CRC). This study aimed to perform a characterisation of CNA and their impact in gene expression.

机译：背景：体细胞拷贝数畸变（CNA）是癌细胞中常见的获得性变化，在结肠癌（结肠直肠癌，CRC）的进展中具有重要作用。这项研究旨在对CNA及其在基因表达中的影响进行表征。

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《British Journal of Cancer》 |2017年第3期|共11页
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M HenarAlonso; SusannaAussó; AdrianaLopez-Doriga; DavidCordero; ElisabetGuinó; XavierSolé; MercèBarenys; Javierde Oca; GabrielCapella; RamónSalazar; RebecaSanz-Pamplona; and VictorMoreno;
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中图分类肿瘤学;
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1. Integrated analysis of genome-wide copy number alterations and gene expression in microsatellite stable, CpG island methylator phenotype-negative colon cancer [J] . LooL.W.M., TiirikainenM., ChengI., Genes, Chromosomes and Cancer . 2013,第5期

机译：综合分析微卫星稳定的CpG岛甲基化表型阴性结肠癌的全基因组拷贝数变化和基因表达
2. Copy number variations in DCC/18q and ERBB2/17q are associated with disease-free survival in microsatellite stable colon cancer [J] . Sefrioui David, Vermeulin Thomas, Blanchard France, International Journal of Cancer =: Journal International du Cancer . 2017,第7期

机译：DCC / 18Q和ERBB2 / 17Q的拷贝数变异与微卫星稳定的结肠癌中无病的存活相关
3. Clinical effects of adjuvant active specific immunotherapy differ between patients with microsatellite-stable and microsatellite-instable colon cancer. [J] . Vincent A de Weger, Annelies W Turksma, Quirinus J M Voorham, Clinical cancer research: an official journal of the American Association for Cancer Research . 2012,第3期

机译：辅助性主动特异性免疫疗法的临床效果在微卫星稳定和微卫星不稳定结肠癌患者之间有所不同。
4. Adjuvant Chemotherapy Should Not Routinely Be Recommended to Patients with Stage II Colon Cancers that Manifest Microsatellite Instability [C] . Sigurdis Haraldsdottir, Richard M. Goldberg Gastrointestinal Cancers Symposium . 2014

机译：不应常规向患有阶段结肠癌的患者常规的辅助化学疗法，表明微卫星不稳定性
5. Integration of copy number aberration and genomic expression data in preinvasive breast cancer [D] . Perry, Victoria Kristina 2012

机译：浸润前乳腺癌中拷贝数畸变和基因组表达数据的整合
6. Comprehensive analysis of copy number aberrations in microsatellite stable colon cancer in view of stromal component [O] . M Henar Alonso, Susanna Aussó, Adriana Lopez-Doriga, 2017

机译：基于基质成分的微卫星稳定结肠癌拷贝数畸变的综合分析
7. Comprehensive analysis of copy number aberrations in microsatellite stable colon cancer in view of stromal component [O] . Alonso, M. Henar, Aussó, Susanna, Lopez-Dóriga, Adriana, 2018

机译：基于基质成分的微卫星稳定结肠癌拷贝数畸变的综合分析

Comprehensive analysis of copy number aberrations in microsatellite stable colon cancer in view of stromal component

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