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The oral VEGF receptor tyrosine kinase inhibitor pazopanib in combination with the MEK inhibitor trametinib in advanced cholangiocarcinoma

机译:口服VEGF受体酪氨酸激酶抑制剂帕唑帕尼联合MEK抑制剂曲美替尼治疗晚期胆管癌

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Correction to: British Journal of Cancer (2017) 116 , 1402–1407; doi: 10.1038/bjc.2017.119 ; published online 25 April 2017 The authors would like to add Dr Rose Parkinson to the author list. She now appears in the author list, and her affiliation is also provided, above. The authors would like to change the acknowledgments to the following: ‘We thank the patients and their families for participating in this study and the clinical staff at Johns Hopkins and MD Anderson Cancer Center for their clinical care and data collection.’ The authors would also like to correct Table 2; the updated table is shown below. To reflect the updated table, the authors would also like to make changes to the ‘Adverse events’ section of the Results. The second sentence of the second paragraph should now read: ‘Treatment-related toxicities were predominantly of mild or moderate severity, with the most common events including rash (76% of patients), hypertension (60%), nausea or vomiting (64%), fatigue (60%), diarrhoea (60%), and thrombocytopenia (40%).’ Despite the changes to Table 2 and the associated text, the authors state that the conclusions put forth in this article, including the safety of this regimen, remain unchanged.
机译:更正为:《英国癌症杂志》(2017)116,1402-1407; doi:10.1038 / bjc.2017.119;在线发表于2017年4月25日。作者希望将Rose Parkinson博士添加到作者列表中。现在,她出现在作者列表中,上面也提供了她的隶属关系。作者想将确认更改为以下内容:“我们感谢患者及其家属参与本研究,以及约翰霍普金斯大学和MD安德森癌症中心的临床工作人员的临床护理和数据收集。”想更正表2;更新后的表如下所示。为了反映更新的表格,作者还希望对结果的“不良事件”部分进行更改。第二段第二句现在应改为:“与治疗有关的毒性主要是轻度或中度,最常见的事件包括皮疹(占患者的76%),高血压(占60%),恶心或呕吐(占64%)。 ),疲劳(60%),腹泻(60%)和血小板减少症(40%)。尽管表2和相关文本有所变化,但作者指出,本文中得出的结论,包括本文的安全性。养生方式,保持不变。

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