Single-nucleotide polymorphisms associated with outcome in metastatic renal cell carcinoma treated with sunitinib

B Beuselinck; A Karadimou; D Lambrechts; B Claes; P Wolter; G Couchy; J Berkers; R Paridaens; P Sch?ffski; A Méjean; V Verkarre; E Lerut; A de la Taille; J-M Tourani; P Bigot; C Linassier; S Négrier; J Berger; J-J Patard; J Zucman-Rossi; S Oudard

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Single-nucleotide polymorphisms associated with outcome in metastatic renal cell carcinoma treated with sunitinib

机译：舒尼替尼治疗转移性肾细胞癌的预后与单核苷酸多态性相关

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Background:There are no validated markers that predict response in metastatic renal cell cancer (RCC) patients treated with sunitinib. We aim to study the impact of single-nucleotide polymorphisms (SNPs) that have recently been proposed as predictors of outcome to anti-VEGF-targeted therapy in metastatic RCC in an independent cohort of patients.

机译：背景：尚无经过验证的可预测舒尼替尼治疗的转移性肾细胞癌（RCC）患者反应的标志物。我们旨在研究单核苷酸多态性（SNPs）的影响，该多核苷酸最近被提出作为独立队列患者在转移性RCC中抗VEGF靶向治疗的预后指标。

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《British Journal of Cancer》 |2013年第4期|共14页
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B Beuselinck; A Karadimou; D Lambrechts; B Claes; P Wolter; G Couchy; J Berkers; R Paridaens; P Sch?ffski; A Méjean; V Verkarre; E Lerut; A de la Taille; J-M Tourani; P Bigot; C Linassier; S Négrier; J Berger; J-J Patard; J Zucman-Rossi; S Oudard;
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1. Association of VEGF and VEGFR2 single nucleotide polymorphisms with hypertension and clinical outcome in metastatic clear cell renal cell carcinoma patients treated with sunitinib [J] . KimJ.J., VaziriS.A.J., RiniB.I., Cancer: A Journal of the American Cancer Society . 2012,第7期

机译：舒尼替尼治疗转移性透明细胞肾细胞癌患者中VEGF和VEGFR2单核苷酸多态性与高血压和临床结局的关系
2. VEGFR1 single nucleotide polymorphisms associated with outcome in patients with metastatic renal cell carcinoma treated with sunitinib - a multicentric retrospective analysis [J] . Beuselinck Benoit, Karadimou Alexandra, Lambrechts Diether, Acta oncologica. . 2014,第1a10期

机译：舒尼替尼治疗转移性肾细胞癌患者VEGFR1单核苷酸多态性与预后相关-多中心回顾性分析
3. Evaluation of polymorphisms in angiogenesis-related genes as predictive and prognostic markers for sunitinib-treated metastatic renal cell carcinoma patients [J] . Dornbusch Juana, Walter Martina, Gottschalk Andrea, Journal of Cancer Research and Clinical Oncology . 2016,第6期

机译：评价舒尼替尼治疗转移性肾细胞癌患者血管生成相关基因的多态性作为预测和预后标志物
4. When to Treat Metastatic Renal Cell Carcinoma Comorbidities, Systemic Therapy, and Active Surveillance in Metastatic Kidney Cancer [C] . Brian I. Rini Genitourinary Cancers Symposium . 2012

机译：何时治疗转移性肾细胞癌的组合，全身治疗，以及在转移性肾癌中的活跃监测
5. Methodological Approaches for Conducting Claims-Based Studies in Patients Diagnosed with Metastatic Renal Cell Carcinoma [D] . Chun, Danielle S. 2021

机译：用于诊断转移性肾细胞癌的患者的基于权利要求的基于权利要求的方法论方法
6. Single-nucleotide polymorphisms associated with outcome in metastatic renal cell carcinoma treated with sunitinib [O] . B Beuselinck, A Karadimou, D Lambrechts, 2013

机译：舒尼替尼治疗转移性肾细胞癌的预后与单核苷酸多态性相关
7. Single-nucleotide polymorphisms associated with outcome in metastatic renal cell carcinoma treated with sunitinib [O] . Beuselinck, Benoit, Karadimou, A, Lambrechts, Diether, 2013

机译：舒尼替尼治疗转移性肾细胞癌的预后与单核苷酸多态性相关

Single-nucleotide polymorphisms associated with outcome in metastatic renal cell carcinoma treated with sunitinib

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