Rhodamine Based Fluorescent Chemosensors for Hg2+ and its Biological Application

摘要

Two new chemosensors, rhodamine 6G derivative bearing hydroxyethyl group (1) and rhodamine base derivative bearing 15-crown-5 group (2) were synthesized and their sensing behaviors toward various metal ions were investigated by UV/Vis and fluorescence spectroscopies. Addition of Hg2+ ion to a CH3CN solution of 1 and 2 gave visual color changes as well as fluorescent OFF-ON observations. Selectivity and sensitivity of 1 towards Hg2+ are excellent enough to detect micromolar level of Hg2+ ion, even in equeous media and biological sample (HeLa cell).