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首页> 外文期刊>BioMed research international >The Use of Stem Cells in Burn Wound Healing: A Review
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The Use of Stem Cells in Burn Wound Healing: A Review

机译:干细胞在烧伤创面愈合中的应用

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摘要

Burn wound healing involves a series of complex processes which are subject to intensive investigations to improve the outcomes, in particular, the healing time and the quality of the scar. Burn injuries, especially severe ones, are proving to have devastating effects on the affected patients. Stem cells have been recently applied in the field to promote superior healing of the wounds. Not only have stem cells been shown to promote better and faster healing of the burn wounds, but also they have decreased the inflammation levels with less scar progression and fibrosis. This review aims to highlight the beneficial therapeutic effect of stem cells in burn wound healing and to discuss the involved pathways and signaling molecules. The review covers various types of burn wound healing like skin and corneal burns, along with the alternative recent therapies being studied in the field of burn wound healing. The current reflection of the attitudes of people regarding the use of stem cells in burn wound healing is also stated.
机译:烧伤伤口愈合涉及一系列复杂的过程,需要进行深入的研究以改善结果,尤其是愈合时间和疤痕质量。烧伤,特别是严重的烧伤,已证明对受影响的患者具有毁灭性影响。干细胞最近已在该领域中应用,以促进伤口的优异愈合。干细胞不仅显示出可以更好,更快地治愈烧伤创面,而且还降低了炎症水平,减少了疤痕的发展和纤维化。这篇综述旨在突出干细胞在烧伤创面愈合中的有益治疗作用,并讨论所涉及的途径和信号分子。该综述涵盖了各种类型的烧伤创面愈合,例如皮肤和角膜烧伤,以及在烧伤创面愈合领域中正在研究的其他替代疗法。还指出了人们对于烧伤创面愈合中使用干细胞的态度的最新反映。

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